{"title": "Just-DNA-Seq", "logoImg": "bafkreia3ei7wli3sstfcpwgivps4hmdeph6hdwwiio5jqvm765ae3wfuju", "website": "https://just-dna.life/", "bannerImg": "bafkreiciyiho4d6xaxfuyo7zwn2xx6dd2332f2rqan3p5obwczmd74uoee", "createdAt": 1681763994346, "userGithub": "antonkulaga", "credentials": {"github": {"type": ["VerifiableCredential"], "proof": {"jws": "eyJhbGciOiJFZERTQSIsImNyaXQiOlsiYjY0Il0sImI2NCI6ZmFsc2V9..S4FEipoKOo0Ni89m8iIIZQRb4a0fXnLoHLZRpB3-7fBi_psjOVJ6dFWMo0U2JrUckxnF0V8B2M5viKtaO0akCw", "type": "Ed25519Signature2018", "created": "2024-08-07T07:54:07.471Z", "proofPurpose": "assertionMethod", "verificationMethod": "did:key:z6MkghvGHLobLEdj1bgRLhS4LPGJAvbMA1tn2zcRyqmYU5LC#z6MkghvGHLobLEdj1bgRLhS4LPGJAvbMA1tn2zcRyqmYU5LC"}, "issuer": "did:key:z6MkghvGHLobLEdj1bgRLhS4LPGJAvbMA1tn2zcRyqmYU5LC", "@context": ["https://www.w3.org/2018/credentials/v1"], "issuanceDate": "2024-08-07T07:54:07.471Z", "expirationDate": "2024-11-05T07:54:07.471Z", "credentialSubject": {"id": "did:pkh:eip155:1:0xBc7BeB2d44Eb0Cddf6c0F2560a21475c2E2aC19C", "hash": "v0.0.0:yOEQJ8CaYutz53Fi5GN0t+q+WBir1+mgRiN49hiLWDc=", "@context": [{"hash": "https://schema.org/Text", "provider": "https://schema.org/Text"}], "provider": "ClearTextGithubOrg#dna-seq#842436"}}, "twitter": {"type": ["VerifiableCredential"], "proof": {"jws": "eyJhbGciOiJFZERTQSIsImNyaXQiOlsiYjY0Il0sImI2NCI6ZmFsc2V9..YGSoT47SDWi-_iXOpF-lvHiuaUDCsY_CUg4ww74S-y22mTSvfW51MOdrQf1fIsWqBq1YYMPg1snbwvVD6QBfBA", "type": "Ed25519Signature2018", "created": "2024-08-07T07:53:31.572Z", "proofPurpose": "assertionMethod", "verificationMethod": "did:key:z6MkghvGHLobLEdj1bgRLhS4LPGJAvbMA1tn2zcRyqmYU5LC#z6MkghvGHLobLEdj1bgRLhS4LPGJAvbMA1tn2zcRyqmYU5LC"}, "issuer": "did:key:z6MkghvGHLobLEdj1bgRLhS4LPGJAvbMA1tn2zcRyqmYU5LC", "@context": ["https://www.w3.org/2018/credentials/v1"], "issuanceDate": "2024-08-07T07:53:31.572Z", "expirationDate": "2024-11-05T07:53:31.572Z", "credentialSubject": {"id": "did:pkh:eip155:1:0xBc7BeB2d44Eb0Cddf6c0F2560a21475c2E2aC19C", "hash": "v0.0.0:Qo4Bg8nrW2ixiW9DwaX6Sbom3mj/8YOSCvgmVDYVos0=", "@context": [{"hash": "https://schema.org/Text", "provider": "https://schema.org/Text"}], "provider": "ClearTextTwitter#just_dna_seq"}}}, "description": "# Just-DNA-Seq: Empowering Individuals with Open-Source Personal Genomics for Longevity\n\n[Just-DNA-Seq](https://just-dna.life/) is an open-source personal genomics platform designed to put individuals in control of their genetic information. Building on earlier Gitcoin-supported efforts, we're seeking additional support to expand the platform—making it even more useful for exploring longevity genetics and advancing decentralized science.\n\nOur goal is to create accessible, transparent tools that help anyone explore what their genome says about their health and longevity.\n\n### Achievements So Far\n\nHere’s what we’ve already built:\n\n* **Open-Source Toolkit:** 23 GitHub repositories form the core of our platform ([GitHub](https://github.com/dna-seq)).\n* **Longevity & Disease Modules:** 11 Oak Var modules focus on genetic insights related to aging and disease risk. (OakVar is an open-source tool for genomic variant analysis.)\n* **Personalized Reports:** We’ve developed open Genetics of Aging and Disease Reports that highlight personal health risks and potential longevity traits ([View Example Report](https://dna-seq.github.io/report_example/)).\n* **Specific Trait Analysis:** Includes a VO2 max trainability genetics module.\n* **AI-Powered Genetic Help:** Genetics Genie, our AI assistant, helps users understand complex genetics. You can try it as a standalone chat ([Chat with Genetics Genie](https://longevity-genie.info/)) or use it as a custom GPT ([Genetics Genie on OpenAI](https://chat.openai.com/g/g-HnvTUyFeq-genetics-genie)).\n* **Community Education:** We’ve hosted workshops and lectures on genetics and large language models (LLMs). ( some of them are available at [our YouTube channel](https://www.youtube.com/@just-dna-seq700) )\n* **Scientific Contribution:** We published a preprint explaining our platform and methods ([arXiv:2403.19087](https://arxiv.org/abs/2403.19087)).\n\n### The Challenges in Personal Genomics – and How We're Solving Them\n\nGenetic data can be powerful, but it’s often locked behind barriers. We’re solving that with transparency, accessibility, and tools that make sense to non-experts.\n\n**1. Transparency and Trust**\n\nMost commercial services operate as black boxes—users don’t know how results are generated or what data is used. Just-DNA-Seq is fully open-source ([Website](https://just-dna.life)), so you can review the code ([GitHub](https://github.com/dna-seq)), run the analysis locally, and understand exactly how each insight is generated. We rely on open databases and give users control to filter and explore their data. And while open tools are the backbone of trust, we’re also working on making them easier to use—better UIs, tutorials, and documentation are part of our ongoing roadmap.\n\n**2. Making Complex Data Understandable**\n\nGenetic data is huge—and messy. While machine learning can spot patterns, it often doesn’t explain *why* they matter. We're actively integrating interpretable AI/ML models that highlight the *why*, linking predictions to genes, pathways, and biological mechanisms. Our aim is to move beyond black-box AI and make genetic insights clear and meaningful for users.\n\n**3. Lowering the Knowledge Barrier**\n\nEven with good tools, genetics can be overwhelming. That’s why we built [Genetics Genie](https://longevity-genie.info/), an AI assistant trained on curated genetic databases and modules. It's available via a web chat or as a custom GPT on OpenAI.\n\nGenetics Genie uses a multi-agent system and supports models like Llama 3.3 and Gemini to provide solid, context-aware answers. We're continuously updating its knowledge base and improving how it explains things in plain language—so users get help, not confusion.\n\n### Help Us Build the Future of Open Personal Genomics\n\nSupporting Just-DNA-Seq on Gitcoin means backing a future where anyone—not just labs or corporations—can understand and explore their own DNA. It’s a step toward a world where personal genomics is open, empowering, and community-driven.\n\nJoin us in building tools that put science into the hands of people.\n\nLet’s democratize personal genomics—together.\n", "logoImgData": {}, "bannerImgData": {}, "projectGithub": "dna-seq", "projectTwitter": "just_dna_seq"}